FGF21 prevents neuronal cell ferroptosis after spinal cord injury by activating the FGFR1/β-Klotho pathway

FGF21 prevents neuronal cell ferroptosis after spinal cord injury by activating the FGFR1/β-Klotho pathway

Spinal cord injury (SCI) is a kind of traumatic nervous system disease caused by neuronal death, causing symptoms like sensory, motor, and autonomic nerve dysfunction. The recovery of neurological function has always been a intractable problem that has greatly distressed individuals and society. Alt...

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Bibliographic Details
Main Authors: Tianli Xu, Qiancheng Zhu, Qun Huang, Qi Gu, Yi Zhu, Mengjie Tang, Shoujin Tian, Liming Wang, Fei Yan, Jianfei Ge, Weiping Sha, Xiaolong Lin
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Brain Research Bulletin
Subjects:
Spinal cord injury
Ferroptosis
RhFGF21
FGFR1
P-FGFR1
β-Klotho
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023001788

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http://www.sciencedirect.com/science/article/pii/S0361923023001788

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