IL-25 blockade inhibits metastasis in breast cancer

Abstract Metastasis is the leading cause of death in breast cancer patients. However, the mechanisms underlying metastasis are not well understood and there is no effective treatment in the clinic. Here, we demonstrate that in MMTV-PyMT, a highly malignant spontaneous breast tumor model, IL-25 (also...

Full description

Bibliographic Details
Main Authors: Zhujun Jiang, Jingtao Chen, Xuemei Du, Hang Cheng, Xiaohu Wang, Chen Dong
Format: Article
Language:English
Published: Oxford University Press 2016-12-01
Series:Protein & Cell
Subjects:
Online Access:http://link.springer.com/article/10.1007/s13238-016-0345-7