Long-term effects of statin treatment in elderly people: extended follow-up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER).

The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER), a placebo-controlled trial of pravastatin, demonstrated a 19% reduction in coronary outcomes (p=0.006) after a mean of 3.2 years, with no impact on stroke outcomes or all-cause mortality. However, there was a suggestion of increa...

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Main Authors: Suzanne M Lloyd, David J Stott, Anton J M de Craen, Patricia M Kearney, Naveed Sattar, Ivan Perry, Christopher J Packard, Andrew Briggs, Laura Marchbank, Harry Comber, J Wouter Jukema, Rudi G J Westendorp, Stella Trompet, Brendan M Buckley, Ian Ford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3759378?pdf=render