HspBP1 is a dual function regulatory protein that controls both DNA repair and apoptosis in breast cancer cells

HspBP1 is a dual function regulatory protein that controls both DNA repair and apoptosis in breast cancer cells

Abstract The Hsp70-binding protein 1 (HspBP1) belongs to a family of co-chaperones that regulate Hsp70 activity and whose biological significance is not well understood. In the present study, we show that when HspBP1 is either knocked down or overexpressed in BRCA1-proficient breast cancer cells, th...

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Bibliographic Details
Main Authors: Cha Kyung Youn, Jung-Hee Lee, Gurusamy Hariharasudhan, Hong Beum Kim, Jeeho Kim, Sumi Lee, Sung-Chul Lim, Sang-Pil Yoon, Sang-Gon Park, In-Youb Chang, Ho Jin You
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04766-0

Internet

https://doi.org/10.1038/s41419-022-04766-0

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