Effect of Phase-Change Nanodroplets and Ultrasound on Blood–Brain Barrier Permeability In Vitro

Effect of Phase-Change Nanodroplets and Ultrasound on Blood–Brain Barrier Permeability In Vitro

Phase-change nanodroplets (PCND;NDs) are emulsions with a perfluorocarbon (PFC) core that undergo acoustic vaporisation as a response to ultrasound (US). Nanodroplets change to microbubbles and cavitate while under the effect of US. This cavitation can apply forces on cell connections in biological...

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Bibliographic Details
Main Authors: Stavros Vlatakis, Weiqi Zhang, Sarah Thomas, Paul Cressey, Alexandru Corneliu Moldovan, Hilde Metzger, Paul Prentice, Sandy Cochran, Maya Thanou
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
nanodroplets
ultrasound
blood-brain barrier
drug delivery
permeability
Online Access:https://www.mdpi.com/1999-4923/16/1/51

Internet

https://www.mdpi.com/1999-4923/16/1/51

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