Cross-reactivity and sequence similarity between microbial transglutaminase and human tissue antigens

Abstract Microbial transglutaminase (mTG) is a bacterial survival factor, frequently used as a food additive to glue processed nutrients. As a result, new immunogenic epitopes are generated that might drive autoimmunity. Presently, its contribution to autoimmunity through epitope similarity and cros...

Full description

Bibliographic Details
Main Authors: Aaron Lerner, Carina Benzvi, Aristo Vojdani
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44452-5