Inhaled 45–50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia

Inhaled 45–50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia

Cooling to 33.5 °C in babies with neonatal encephalopathy significantly reduces death and disability, however additional therapies are needed to maximize brain protection. Following hypoxia–ischemia we assessed whether inhaled 45–50% Argon from 2–26 h augmented hypothermia neuroprotection in a neona...

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Bibliographic Details
Main Authors: Kevin D. Broad, Igor Fierens, Bobbi Fleiss, Eridan Rocha-Ferreira, Mojgan Ezzati, Jane Hassell, Daniel Alonso-Alconada, Alan Bainbridge, Go Kawano, Daqing Ma, Ilias Tachtsidis, Pierre Gressens, Xavier Golay, Robert D. Sanders, Nicola J. Robertson
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Neurobiology of Disease
Subjects:
Argon
Neonatal encephalopathy
Therapeutic hypothermia
Noble gas
Hypoxia–ischemia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115301030

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http://www.sciencedirect.com/science/article/pii/S0969996115301030

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