Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

Non-autonomous cell-death is a cardinal feature of the disintegration of neural networks in neurodegenerative diseases, but the molecular bases of this process are poorly understood. The neural retina comprises a mosaic of rod and cone photoreceptors. Cone and rod photoreceptors degenerate upon rod-...

Full description

Bibliographic Details
Main Authors: Kyoung-In Cho, Mdemdadul Haque, Jessica Wang, Minzhong Yu, Ying Hao, Sunny Qiu, Indulekha C L Pillai, Neal S Peachey, Paulo A Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3688534?pdf=render

Internet

http://europepmc.org/articles/PMC3688534?pdf=render

Similar Items