Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes

Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes

The lymphatic system plays a crucial role in immunity and lymph nodes (LNs) undergo drastic remodeling during inflammation. Here, we used single-cell RNA sequencing to investigate transcriptional changes in lymphatic endothelial cells (LECs) in LNs draining naïve and inflamed skin. We found that sub...

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Bibliographic Details
Main Authors: Eliane Sibler, Yuliang He, Luca Ducoli, Nadja Keller, Noriki Fujimoto, Lothar C. Dieterich, Michael Detmar
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
scRNA-seq
inflammation
lymph node
lymphatic endothelial cells
Online Access:https://www.mdpi.com/2073-4409/10/6/1371

Internet

https://www.mdpi.com/2073-4409/10/6/1371

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