Efficient Oxidative Dearomatisations of Substituted Phenols Using Hypervalent Iodine (III) Reagents and Antiprotozoal Evaluation of the Resulting Cyclohexadienones against <i>T. b. rhodesiense</i> and <i>P. falciparum</i> Strain NF54

Efficient Oxidative Dearomatisations of Substituted Phenols Using Hypervalent Iodine (III) Reagents and Antiprotozoal Evaluation of the Resulting Cyclohexadienones against <i>T. b. rhodesiense</i> and <i>P. falciparum</i> Strain NF54

Quinones and quinols are secondary metabolites of higher plants that are associated with many biological activities. The oxidative dearomatization of phenols induced by hypervalent iodine(III) reagents has proven to be a very useful synthetic approach for the preparation of these compounds, which ar...

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Bibliographic Details
Main Authors: Nina Scheiber, Gregor Blaser, Eva-Maria Pferschy-Wenzig, Marcel Kaiser, Pascal Mäser, Armin Presser
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
oxidative dearomatization
hypervalent iodine
cyclohexadienones
antiprotozoal activity
physicochemical parameters
Online Access:https://www.mdpi.com/1420-3049/27/19/6559

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https://www.mdpi.com/1420-3049/27/19/6559

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