Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons

Summary: Generation of functional human dopaminergic (DA) neurons from human induced pluripotent stem cells (hiPSCs) is a crucial tool for modeling dopamine-related human diseases and cell replacement therapies. Here, we present a protocol to combine neuralizing transcription factor (NGN2) programmi...

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Bibliographic Details
Main Authors: Razan Sheta, Maxime Teixeira, Walid Idi, Abid Oueslati
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723004537