Listeria monocytogenes GshF contributes to oxidative stress tolerance via regulation of the phosphoenolpyruvate-carbohydrate phosphotransferase system

ABSTRACT Glutathione (GSH) is an essential component of the glutaredoxin (Grx) system, and it is synthesized by the enzyme glutathione synthase GshF in Listeria monocytogenes. GSH plays a crucial role in regulating Listeria virulence by modifying the virulence factors LLO and PrfA. In this study, we...

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Bibliographic Details
Main Authors: Mianmian Chen, Jiaxue Zhang, Jing Xia, Jing Sun, Xian Zhang, Jiali Xu, Simin Deng, Yue Han, Lingli Jiang, Houhui Song, Changyong Cheng
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.02365-23