Synthesis of Novel Diterpenic Peptides via the Ugi Reaction and Their Anticancer Activities

Novel diterpenic peptide derivatives were synthesized via the Ugi four-component reaction at ambient temperature. The protocol employed a reaction between formaldehyde, benzyl amine, the corresponding diterpene acid, and ethyl 2-isocyanoacetate. The anticancer properties of the compounds were studie...

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Bibliographic Details
Main Authors: Anna A. Smirnova, Liana M. Zakirova, Irina E. Smirnova, Elena V. Tretyakova
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2023/3/M1707