Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons

<p>Abstract</p> <p>Prostaglandin E2 (PGE2) is a well-known inflammatory mediator that enhances the excitability of DRG neurons. Homomeric P2X3 and heteromeric P2X2/3 receptors are abundantly expressed in dorsal root ganglia (DRG) neurons and participate in the transmission of nocic...

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Bibliographic Details
Main Authors: Huang Li-Yen, Li Guang-Wen, Wang Congying
Format: Article
Language:English
Published: SAGE Publishing 2007-08-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/3/1/22