Knockdown of MRPL35 promotes cell apoptosis and inhibits cell proliferation in non-small-cell lung cancer

Knockdown of MRPL35 promotes cell apoptosis and inhibits cell proliferation in non-small-cell lung cancer

Abstract Background Non-small cell lung cancer (NSCLC) is a major pathological type of lung cancer. However, its pathogenesis remains largely unclear. MRPL35 is a regulatory subunit of the mitoribosome, which can regulate the assembly of cytochrome c oxidases and plays an important role in the occur...

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Bibliographic Details
Main Authors: Chengling Zhao, Lei Chen, Zhixin Jin, Haitao Liu, Chao Ma, Hangtian Zhou, Lingling Xu, Sihui Zhou, Yan Shi, Wei Li, Yuqing Chen, Chengli Dou, Xiaojing Wang
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Pulmonary Medicine
Subjects:
MRPL35
NSCLC
Proliferation
Apoptosis
p53
Online Access:https://doi.org/10.1186/s12890-023-02677-0

Internet

https://doi.org/10.1186/s12890-023-02677-0

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