The nutraceutical electrophile scavenger 2-hydroxybenzylamine (2-HOBA) attenuates gastric cancer development caused by Helicobacter pylori

The nutraceutical electrophile scavenger 2-hydroxybenzylamine (2-HOBA) attenuates gastric cancer development caused by Helicobacter pylori

Stomach cancer is a leading cause of cancer death. Helicobacter pylori is a bacterial gastric pathogen that is the primary risk factor for carcinogenesis, associated with its induction of inflammation and DNA damage. Dicarbonyl electrophiles are generated from lipid peroxidation during the inflammat...

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Bibliographic Details
Main Authors: Alain P. Gobert, Mohammad Asim, Thaddeus M. Smith, Kamery J. Williams, Daniel P. Barry, Margaret M. Allaman, Kara M. McNamara, Caroline V. Hawkins, Alberto G. Delgado, M. Blanca Piazuelo, John A. Rathmacher, Keith T. Wilson
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Electrophiles
Reactive aldehyde
Oxidative damage
Gastritis
Gastric cancer
DNA damage
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222014810

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http://www.sciencedirect.com/science/article/pii/S0753332222014810

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