Minimizing the Anticodon-Recognized Loop of <i>Methanococcus jannaschii</i> Tyrosyl-tRNA Synthetase to Improve the Efficiency of Incorporating Noncanonical Amino Acids

Minimizing the Anticodon-Recognized Loop of <i>Methanococcus jannaschii</i> Tyrosyl-tRNA Synthetase to Improve the Efficiency of Incorporating Noncanonical Amino Acids

In the field of genetic code expansion (GCE), improvements in the efficiency of noncanonical amino acid (ncAA) incorporation have received continuous attention. By analyzing the reported gene sequences of giant virus species, we noticed some sequence differences at the tRNA binding interface. On the...

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Bibliographic Details
Main Authors: Zhiyang Hu, Jinming Liang, Taogeng Su, Di Zhang, Hao Li, Xiangdong Gao, Wenbin Yao, Xiaoda Song
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomolecules
Subjects:
genetic code expansion
giant virus
anticodon recognition
loop minimization
noncanonical amino acids
Online Access:https://www.mdpi.com/2218-273X/13/4/610

Internet

https://www.mdpi.com/2218-273X/13/4/610

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