A mathematical model of cytotoxic and helper T cell interactions in a tumour microenvironment

We develop a mathematical model to examine the role of helper and cytotoxic T cells in an anti-tumour immune response. The model comprises three ordinary differential equations describing the dynamics of the tumour cells, the helper and the cytotoxic T cells, and implicitly accounts for immunosuppre...

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Bibliographic Details
Main Authors: Heidi Dritschel, Sarah L. Waters, Andreas Roller, Helen M. Byrne
Format: Article
Language:English
Published: Intercollegiate Biomathematics Alliance 2018-06-01
Series:Letters in Biomathematics
Subjects:
Online Access:http://dx.doi.org/10.1080/23737867.2018.1465863