New Non-Toxic <i>N</i>-alkyl Cholinium-Based Ionic Liquids as Excipients to Improve the Solubility of Poorly Water-Soluble Drugs

New Non-Toxic <i>N</i>-alkyl Cholinium-Based Ionic Liquids as Excipients to Improve the Solubility of Poorly Water-Soluble Drugs

In this work, we prepared new biocompatible <i>N</i>-alkyl cholinium-based ionic liquids to be used as cosolvents to improve the solubility of poorly water-soluble drugs, namely, sodium diclofenac and paracetamol. In this set of ionic liquids, we intend to understand the effect of increa...

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Bibliographic Details
Main Authors: Ana R. Jesus, Luís R. Raposo, Mário R. C. Soromenho, Daniela A. S. Agostinho, José M. S. S. Esperança, Pedro V. Baptista, Alexandra R. Fernandes, Patrícia M. Reis
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Symmetry
Subjects:
ionic liquids
bioavailability
oral drugs
drug delivery
cytotoxicity
Online Access:https://www.mdpi.com/2073-8994/13/11/2053

Internet

https://www.mdpi.com/2073-8994/13/11/2053

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