A shared transcriptional code orchestrates temporal patterning of the central nervous system.
The molecular mechanisms that produce the full array of neuronal subtypes in the vertebrate nervous system are incompletely understood. Here, we provide evidence of a global temporal patterning program comprising sets of transcription factors that stratifies neurons based on the developmental time a...
Main Authors: | Andreas Sagner, Isabel Zhang, Thomas Watson, Jorge Lazaro, Manuela Melchionda, James Briscoe |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-11-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3001450 |
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