Dapagliflozin promotes angiogenesis in hindlimb ischemia mice by inducing M2 macrophage polarization

Critical limb ischemia (CLI) is associated with a higher risk of limb amputation and cardiovascular death. Dapagliflozin has shown great potential in the treatment of cardiovascular disease. However, the effects of dapagliflozin on CLI and the underlying mechanisms have not been fully elucidated. We...

Full description

Bibliographic Details
Main Authors: Heng Yang, Wanqi Lan, Wu Liu, Tingtao Chen, Yanhua Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1255904/full