An automated protocol for modelling peptide substrates to proteases

Abstract Background Proteases are key drivers in many biological processes, in part due to their specificity towards their substrates. However, depending on the family and molecular function, they can also display substrate promiscuity which can also be essential. Databases compiling specificity mat...

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Bibliographic Details
Main Authors: Rodrigo Ochoa, Mikhail Magnitov, Roman A. Laskowski, Pilar Cossio, Janet M. Thornton
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-020-03931-6