Survival of the simplest in microbial evolution

In asexual populations selection at different genomic loci can interfere with each other. Here, using a biophysical model of molecular evolution the authors show that interference results in long-term degradation of molecular function, an effect that strongly depends on genome size.

Bibliographic Details
Main Authors: Torsten Held, Daniel Klemmer, Michael Lässig
Format: Article
Language:English
Published: Nature Portfolio 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10413-8