Evaluation of the Association between Single Nucleotide Polymorphisms of Metabolizing Enzymes with the Serum Concentration of Paracetamol and Its Metabolites

Intravenous paracetamol is a commonly administered analgesic and antipyretic in inpatient settings. Paracetamol is metabolized by cytochrome P450 (CYP) enzymes followed by conjugating enzymes to mainly glucuronide but to a lesser extent, sulphate metabolites, and oxidative metabolites. Single nucleo...

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Bibliographic Details
Main Authors: Kannan Sridharan, Ali Mohamed Qader, Mustafa Hammad, Anfal Jassim, Diab Eltayeb Diab, Betsy Abraham, Hasan M. S. N. Hasan, Sheikh Abdul Azeez Pasha, Shamik Shah
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/12/1235