Dynamics of T-Lymphocyte Activation Related to Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in Persons With Advanced HIV

Dynamics of T-Lymphocyte Activation Related to Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in Persons With Advanced HIV

Most persons living with HIV (PLWH) experience a significant restoration of their immunity associated with successful inhibition of viral replication after antiretroviral therapy (ART) initiation. Nevertheless, with the robust quantitative and qualitative restoration of CD4+ T-lymphocytes, a fractio...

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Bibliographic Details
Main Authors: Rafael Tibúrcio, Beatriz Barreto-Duarte, Gopolan Naredren, Artur T. L. Queiroz, Selvaraj Anbalagan, Kaustuv Nayak, Narayanan Ravichandran, Rajasekaran Subramani, Lis R. V. Antonelli, Kumar Satagopan, Komathi Anbalagan, Brian O. Porter, Alan Sher, Soumya Swaminathan, Irini Sereti, Bruno B. Andrade
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
T lymphocytes
IRIS pathogenesis
TB-HIV coinfection
inflammation
T cell activation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.757843/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.757843/full

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