Amino acid deprivation induces AKT activation by inducing GCN2/ATF4/REDD1 axis
Abstract Amino acid availability is sensed by various signaling molecules, including general control nonderepressible 2 (GCN2) and mechanistic target of rapamycin complex 1 (mTORC1). However, it is unclear how these sensors are associated with cancer cell survival under low amino acid availability....
| Váldodahkkit: | , , , , |
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| Materiálatiipa: | Artihkal |
| Giella: | English |
| Almmustuhtton: |
Nature Publishing Group
2021-12-01
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| Ráidu: | Cell Death and Disease |
| Liŋkkat: | https://doi.org/10.1038/s41419-021-04417-w |