The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications

The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications

Increasing evidence links the RAGE (receptor for advanced glycation end products)/DIAPH1 (Diaphanous 1) signaling axis to the pathogenesis of diabetic complications. RAGE is a multi-ligand receptor and through these ligand–receptor interactions, extensive maladaptive effects are exerted on cell type...

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Bibliographic Details
Main Authors: Ravichandran Ramasamy, Alexander Shekhtman, Ann Marie Schmidt
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
RAGE
DIAPH1
interferon pathway
diabetes
diabetic complications
small molecule antagonist
Online Access:https://www.mdpi.com/1422-0067/23/9/4579

Internet

https://www.mdpi.com/1422-0067/23/9/4579

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