Induction and Amelioration of Methotrexate-Induced Gastrointestinal Toxicity are Related to Immune Response and Gut MicrobiotaResearch in context

As a widely used anticancer and immunosuppressive agent, methotrexate (MTX) can induce multiple adverse drug reactions (ADRs), such as gastrointestinal toxicity, the mechanisms are poorly understood. Gut microbiota has been widely reported to be associated with the onset of multiple diseases as well...

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Bibliographic Details
Main Authors: Bailing Zhou, Xuyang Xia, Peiqi Wang, Shuang Chen, Chaoheng Yu, Rong Huang, Rui Zhang, Yantai Wang, Lian Lu, Fengjiao Yuan, Yaomei Tian, Yingzi Fan, Xueyan Zhang, Yang Shu, Shouyue Zhang, Ding Bai, Lei Wu, Heng Xu, Li Yang
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418302366