The Construction of Polycyclic Pyridones via Ring-Opening Transformations of 3-hydroxy-3,4-dihydropyrido[2,1-<i>c</i>][1,4]oxazine-1,8-diones

The Construction of Polycyclic Pyridones via Ring-Opening Transformations of 3-hydroxy-3,4-dihydropyrido[2,1-<i>c</i>][1,4]oxazine-1,8-diones

This work describes the synthesis of 3-hydroxy-3,4-dihydropyrido[2,1-<i>c</i>][1,4]oxazine-1,8-diones, their tautomerism, and reactivity towards binucleophiles. These molecules are novel and convenient building-blocks for the direct construction of biologically important polycyclic pyrid...

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Bibliographic Details
Main Authors: Viktoria V. Viktorova, Elena V. Steparuk, Dmitrii L. Obydennov, Vyacheslav Y. Sosnovskikh
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
4-pyridone
oxazinone
ring-opening
benzimidazole
aldehyde-lactol tautomerism
ammonium acetate
Online Access:https://www.mdpi.com/1420-3049/28/3/1285

Internet

https://www.mdpi.com/1420-3049/28/3/1285

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