Chemoproteomic identification of molecular targets of antifungal prototypes, thiosemicarbazide and a camphene derivative of thiosemicarbazide, in Paracoccidioides brasiliensis.

Chemoproteomic identification of molecular targets of antifungal prototypes, thiosemicarbazide and a camphene derivative of thiosemicarbazide, in Paracoccidioides brasiliensis.

Paracoccidioidomycosis (PCM) is a neglected human systemic disease caused by species of the genus Paracoccidioides. The disease attacks the host's lungs and may disseminate to many other organs. Treatment involves amphotericin B, sulfadiazine, trimethoprim-sulfamethoxazole, itraconazole, ketoco...

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Bibliographic Details
Main Authors: Joyce Villa Verde Bastos Borba, Sinji Borges Ferreira Tauhata, Cecília Maria Alves de Oliveira, Monique Ferreira Marques, Alexandre Melo Bailão, Célia Maria de Almeida Soares, Maristela Pereira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6110461?pdf=render

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http://europepmc.org/articles/PMC6110461?pdf=render

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