RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-α secretion

RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-α secretion

Studies of the response of RAW264.7 cells (RAW) to lipopolysaccharide (LPS) were carried out to determine why these cells do not demonstrate the prostaglandin (PG)-dependent autocrine regulation of tumor necrosis factor-α (TNF-α) secretion observed in primary resident peritoneal macrophages (RPMs)....

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Bibliographic Details
Main Authors: Carol A. Rouzer, Aaron T. Jacobs, Chetan S. Nirodi, Philip J. Kingsley, Jason D. Morrow, Lawrence J. Marnett
Format: Article
Language:English
Published: Elsevier 2005-05-01
Series:Journal of Lipid Research
Subjects:
macrophage
lipopolysaccharide
cyclooxygenase-1
cyclooxygenase-2
arachidonic acid
cytosolic phospholipase A2
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339869

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http://www.sciencedirect.com/science/article/pii/S0022227520339869

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