Bioinformatical Study and Evaluation of Expression of Cholera Toxin Subunit B Optimized Gene as a Vaccine Candidate

Background: Cholera is a lethal diarrheal disease caused by Vibrio cholerae. Cholera toxin is the major virulence factor in pathogenesis of Vibrio cholerae. The B subunit of the enterotoxin, which is responsible for toxin binding to eukaryotic cells, has immunogenic properties. The aim of this study...

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Bibliographic Details
Main Authors: Shahram Nazarian, Mohhamad Ali Arefpour, Mohhamd Javad Bagheripour, Golamreza Olad
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2014-05-01
Series:مجله دانشکده پزشکی اصفهان
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Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/3777