Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents

Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents

Two practical and efficient approaches have been implemented as alternative procedures for the synthesis of naftifine and novel diversely substituted analogues 16 and 20 in good to excellent yields, mediated by Mannich-type reactions as the key step of the processes. In these approaches, the γ-amino...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Rodrigo Abonia, Alexander Garay, Juan C. Castillo, Braulio Insuasty, Jairo Quiroga, Manuel Nogueras, Justo Cobo, Estefanía Butassi, Susana Zacchino
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: MDPI AG 2018-02-01
Ráidu:Molecules
Fáttát:
benzylamines
propiophenone salts
γ-aminoalcohols
Mannich-type reaction
allyamines
naftifine analogues
antifungal activity
Liŋkkat:http://www.mdpi.com/1420-3049/23/3/520

Interneahtta

http://www.mdpi.com/1420-3049/23/3/520

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