An approach for elucidating dermal fibroblast dedifferentiation in amphibian limb regeneration

An approach for elucidating dermal fibroblast dedifferentiation in amphibian limb regeneration

Abstract Urodele amphibians, Pleurodeles waltl and Ambystoma mexicanum, have organ-level regeneration capability, such as limb regeneration. Multipotent cells are induced by an endogenous mechanism in amphibian limb regeneration. It is well known that dermal fibroblasts receive regenerative signals...

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Bibliographic Details
Main Authors: Akira Satoh, Rena Kashimoto, Ayaka Ohashi, Saya Furukawa, Sakiya Yamamoto, Takeshi Inoue, Toshinori Hayashi, Kiyokazu Agata
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Zoological Letters
Subjects:
Pde4b
Limb regeneration
Pleurodels waltl
Ambystoma mexicanum
Dedifferentiation
Reprogramming
Online Access:https://doi.org/10.1186/s40851-022-00190-6

Internet

https://doi.org/10.1186/s40851-022-00190-6

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