Robust radiosensitization of hemoglobin-curcumin nanoparticles suppresses hypoxic hepatocellular carcinoma

Abstract Background Radioresistance inducing by hypoxic microenvironment of hepatocellular carcinoma is a major obstacle to clinical radiotherapy. Advanced nanomedicine provides an alternative to alleviate the hypoxia extent of solid tumor, even to achieve effective synergistic treatment when combin...

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Bibliographic Details
Main Authors: Ruoling Gao, Yuan Gu, Ying Yang, Yuping He, Wenpeng Huang, Ting Sun, Zaixiang Tang, Yong Wang, Wei Yang
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-022-01316-w