Chemoenzymatic site-specific labeling of influenza glycoproteins as a tool to observe virus budding in real time.

The influenza virus uses the hemagglutinin (HA) and neuraminidase (NA) glycoproteins to interact with and infect host cells. While biochemical and microscopic methods allow examination of the early steps in flu infection, the genesis of progeny virions has been more difficult to follow, mainly becau...

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Bibliographic Details
Main Authors: Maximilian Wei-Lin Popp, Roos A Karssemeijer, Hidde L Ploegh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3310791?pdf=render