Chemoenzymatic site-specific labeling of influenza glycoproteins as a tool to observe virus budding in real time.
The influenza virus uses the hemagglutinin (HA) and neuraminidase (NA) glycoproteins to interact with and infect host cells. While biochemical and microscopic methods allow examination of the early steps in flu infection, the genesis of progeny virions has been more difficult to follow, mainly becau...
Main Authors: | Maximilian Wei-Lin Popp, Roos A Karssemeijer, Hidde L Ploegh |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3310791?pdf=render |
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