<i>In Vivo</i> Models and <i>In Vitro</i> Assays for the Assessment of Pertussis Toxin Activity
One of the main virulence factors produced by <i>Bordetella pertussis</i> is pertussis toxin (PTx) which, in its inactivated form, is the major component of all marketed acellular pertussis vaccines. PTx ADP ribosylates Gα<sub>i</sub> proteins, thereby affecting the inhibitio...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Toxins |
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| Online Access: | https://www.mdpi.com/2072-6651/13/8/565 |