Dual regulation of osteosarcoma hypoxia microenvironment by a bioinspired oxygen nanogenerator for precise single-laser synergistic photodynamic/photothermal/induced antitumor immunity therapy

Dual regulation of osteosarcoma hypoxia microenvironment by a bioinspired oxygen nanogenerator for precise single-laser synergistic photodynamic/photothermal/induced antitumor immunity therapy

The hypoxic tumor microenvironment (TME) of osteosarcoma (OS) is the Achilles’ heel of oxygen-dependent photodynamic therapy (PDT), and tremendous challenges are confronted to reverse the hypoxia. Herein, we proposed a ''reducing expenditure of O2 and broadening sources'' dual-st...

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Bibliographic Details
Main Authors: Chongqing Zhang, Dongsheng Li, Xin Zhang, Rong Dai, Weiwei Kang, Yao Li, Qin Liu, Mengting Gao, Ziliang Zheng, Ruiping Zhang, Zhaohui Wen
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Materials Today Bio
Subjects:
Osteosarcoma
Hypoxia
Nanogenerators
Dual-strategy
PDT
PTT
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424001133

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http://www.sciencedirect.com/science/article/pii/S2590006424001133

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