Signal transduction in neurons: effects of cellular prion protein on fyn kinase and ERK1/2 kinase

<p>Abstract</p> <p>Background</p> <p>It has been reported that cellular prion protein (PrP<sup>c</sup>) co-localizes with caveolin-1 and participates to signal transduction events by recruiting Fyn kinase. As PrP<sup>c</sup> is a secreted protein...

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Bibliographic Details
Main Author: Tomasi Vittorio
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Immunity & Ageing
Online Access:http://www.immunityageing.com/content/7/S1/S5