Plasma membrane mechanical stress activates TRPC5 channels.

Mechanical forces exerted on cells impose stress on the plasma membrane. Cells sense this stress and elicit a mechanoelectric transduction cascade that initiates compensatory mechanisms. Mechanosensitive ion channels in the plasma membrane are responsible for transducing the mechanical signals to el...

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Bibliographic Details
Main Authors: Bing Shen, Ching-On Wong, On-Chai Lau, Theodosia Woo, Suwen Bai, Yu Huang, Xiaoqiang Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388645?pdf=render