Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes

Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes

Summary: Cytotoxin-associated gene A (CagA) of Helicobacter pylori (Hp) may promote immune evasion of Hp-infected gastric cancer (GC), but potential mechanisms are still under explored. In this study, the positive rates of CagA and PD-L1 protein in tumor tissues and the high level of exosomal PD-L1...

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Bibliographic Details
Main Authors: Jinfeng Wang, Rilin Deng, Shuai Chen, Shun Deng, Qi Hu, Biaoming Xu, Junjun Li, Zhuo He, Mingjing Peng, Sanlin Lei, Tiexiang Ma, Zhuo Chen, Haizhen Zhu, Chaohui Zuo
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Gastroenterology
Microbiology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223024914

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223024914

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