Parasitic infections related to anti-type 2 immunity monoclonal antibodies: a disproportionality analysis in the food and drug administration’s adverse event reporting system (FAERS)

Parasitic infections related to anti-type 2 immunity monoclonal antibodies: a disproportionality analysis in the food and drug administration’s adverse event reporting system (FAERS)

Introduction: Monoclonal antibodies (mAbs) targeting immunoglobulin E (IgE) [omalizumab], type 2 (T2) cytokine interleukin (IL) 5 [mepolizumab, reslizumab], IL-4 Receptor (R) α [dupilumab], and IL-5R [benralizumab]), improve quality of life in patients with T2-driven inflammatory diseases. However,...

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Bibliographic Details
Main Authors: Victor Pera, Guy G. Brusselle, Sebastian Riemann, Jan A. Kors, Erik M. Van Mulligen, Rowan Parry, Marcel de Wilde, Peter R. Rijnbeek, Katia M. C. Verhamme
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
biologicals
monoclonal antibodies
disproportionality analysis
parasitic infections
spontaneous reporting
FAERS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1276340/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1276340/full

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