Regulation of mitochondrial dynamics in 2-methoxyestradiol-mediated osteosarcoma cell death

Abstract Osteosarcoma (OS) is one of the most malignant tumors of childhood and adolescence. Research on mitochondrial dynamics (fusion/fission) and biogenesis has received much attention in last few years, as they are crucial for death of cancer cells. Specifically, it was shown that increased expr...

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Bibliographic Details
Main Authors: Magdalena Gorska-Ponikowska, Paulina Bastian, Agata Zauszkiewicz-Pawlak, Agata Ploska, Adrian Zubrzycki, Alicja Kuban-Jankowska, Stephan Nussberger, Leszek Kalinowski, Zbigniew Kmiec
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80816-x