Mitochondrial permeability transition pore contributes to mitochondrial dysfunction in fibroblasts of patients with sporadic Alzheimer's disease

In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a neurodegenerative disorder, mitochondrial damage is also present in patients’ peripheral tissues, suggesting a target to develop new biomarkers...

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Bibliographic Details
Main Authors: María José Pérez, Daniela P. Ponce, Alejandra Aranguiz, Maria I. Behrens, Rodrigo A. Quintanilla
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171830627X