Mitochondrial permeability transition pore contributes to mitochondrial dysfunction in fibroblasts of patients with sporadic Alzheimer's disease
In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a neurodegenerative disorder, mitochondrial damage is also present in patients’ peripheral tissues, suggesting a target to develop new biomarkers...
Main Authors: | María José Pérez, Daniela P. Ponce, Alejandra Aranguiz, Maria I. Behrens, Rodrigo A. Quintanilla |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-10-01
|
Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221323171830627X |
Similar Items
-
Mitochondrial Dysfunction and Alterations in Mitochondrial Permeability Transition Pore (mPTP) Contribute to Apoptosis Resistance in Idiopathic Pulmonary Fibrosis Fibroblasts
by: Erika Rubí Luis-García, et al.
Published: (2021-07-01) -
Activation of the Nrf2 Pathway Prevents Mitochondrial Dysfunction Induced by Caspase-3 Cleaved Tau: Implications for Alzheimer’s Disease
by: Francisca Villavicencio-Tejo, et al.
Published: (2022-03-01) -
Mitochondrial Permeability Transition: A Pore Intertwines Brain Aging and Alzheimer’s Disease
by: Kun Jia, et al.
Published: (2021-03-01) -
The Reduction in the Mitochondrial Membrane Potential in Aging: The Role of the Mitochondrial Permeability Transition Pore
by: Hagai Rottenberg
Published: (2023-08-01) -
Regulation of mitochondrial permeability transition pore by PINK1
by: Gautier Clement A, et al.
Published: (2012-05-01)