Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes

Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes

Objective: Storage of triglycerides in lipid droplets is governed by a set of lipid droplet-associated proteins. One of these lipid droplet-associated proteins, hypoxia-inducible lipid droplet-associated (HILPDA), was found to impair lipid droplet breakdown in macrophages and cancer cells by inhibit...

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Bibliographic Details
Main Authors: Montserrat A. de la Rosa Rodriguez, Lei Deng, Anne Gemmink, Michel van Weeghel, Marie Louise Aoun, Christina Warnecke, Rajat Singh, Jan Willem Borst, Sander Kersten
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Molecular Metabolism
Subjects:
Lipid droplets
Liver
HILPDA
DGAT1
Fluorescence microscopy
Triglyceride synthesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821000089

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http://www.sciencedirect.com/science/article/pii/S2212877821000089

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