Dual function of the Leon/USP5 deubiquitinase in the ubiquitin-proteasome and autophagic pathways

ABSTRACTThe ubiquitin-proteasome system (UPS) and autophagy are highly conserved processes that maintain cellular health through the clearance of misfolded/aberrant proteins and damaged organelles. Ubiquitination is a crucial protein modification to regulate entry in these two pathways. However, the...

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Bibliographic Details
Main Authors: Yuchieh Jay Lin, Guang-Chao Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Autophagy Reports
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/27694127.2023.2278299