Pan-Cancer analysis shows that ACO2 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including hepatocellular carcinoma

Pan-Cancer analysis shows that ACO2 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including hepatocellular carcinoma

BackgroundRecent evidence increasingly suggests key roles for the tricarboxylic acid cycle and fatty acid metabolism in tumor progression and metastasis. Aconitase 2 (ACO2) is a component of the tricarboxylic acid cycle and represents a key cellular metabolic hub that promotes de novo fatty acid bio...

Full description

Bibliographic Details
Main Authors: Zhen Wang, Wanqun Zheng, Zhen Chen, Shilun Wu, Haoxiao Chang, Ming Cai, Heping Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
ACO2
pan-cancer
prognosis
immune infiltration
hepatocellular carcinoma
lipidomics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1055376/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1055376/full

Similar Items