Comparative Blood Profiling Based on ATR-FTIR Spectroscopy and Chemometrics for Differential Diagnosis of Patients with Amyotrophic Lateral Sclerosis—Pilot Study

Comparative Blood Profiling Based on ATR-FTIR Spectroscopy and Chemometrics for Differential Diagnosis of Patients with Amyotrophic Lateral Sclerosis—Pilot Study

Amyotrophic lateral sclerosis (ALS) is a motor neurodegenerative disease characterized by poor prognosis. Currently, screening and diagnostic methods for ALS remain challenging, often leading to diagnosis at an advanced stage of the disease. This delay hinders the timely initiation of therapy, negat...

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Bibliographic Details
Main Authors: Kateryna Tkachenko, José M. González-Saíz, Ana C. Calvo, Christian Lunetta, Rosario Osta, Consuelo Pizarro
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biosensors
Subjects:
amyotrophic lateral sclerosis
infrared spectroscopy
metabolic signatures
patient stratification
chemometrics
classification strategy
Online Access:https://www.mdpi.com/2079-6374/14/11/526

Internet

https://www.mdpi.com/2079-6374/14/11/526

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